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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF11 All Species: 20.3
Human Site: T502 Identified Species: 27.92
UniProt: P52732 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52732 NP_004514.2 1056 119159 T502 A A S K L L N T V E E T T K D
Chimpanzee Pan troglodytes XP_507923 1056 119132 T502 A A S K L L N T V E E T T K D
Rhesus Macaque Macaca mulatta XP_001087644 853 96218 I333 G R T R T S I I A T I S P A S
Dog Lupus familis XP_534964 1334 149091 T784 A A S R L L T T V E E T T K D
Cat Felis silvestris
Mouse Mus musculus Q6P9P6 1052 118008 T501 T A S K L L N T V K E T T R A
Rat Rattus norvegicus O55165 796 89797 G276 T A G G G G G G G G T S G S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 Q474 E V I R N L Q Q V L A Q F Q S
Frog Xenopus laevis P28025 1060 119314 T495 T A N K L L S T V R E T T R D
Zebra Danio Brachydanio rerio NP_775368 955 106984 I435 T E E E L K K I I D L F T D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46863 1066 121145 A506 Q A Q E I L A A A D L A T D D
Honey Bee Apis mellifera XP_623508 706 80766 V186 D P T K K G A V I V H G L E E
Nematode Worm Caenorhab. elegans P46873 699 78760 P179 M H V C H D V P A C K E L M T
Sea Urchin Strong. purpuratus P46872 699 78679 K179 P D V G V Y V K D L S A F V V
Poplar Tree Populus trichocarpa XP_002314206 1066 119757 S520 F I S N L L K S E K G L V E R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 S495 I I S E Q K K S E N V L V Q Q
Baker's Yeast Sacchar. cerevisiae P28742 1111 125776 N554 S Q K Q Y N T N Q N M Q L K I
Red Bread Mold Neurospora crassa P48467 928 102392 S408 T A R P S T P S R L L P E S R
Conservation
Percent
Protein Identity: 100 99.8 77.5 69.3 N.A. 79.7 23.3 N.A. N.A. 25.3 56.2 47.7 N.A. 33.5 37.1 27.4 29.2
Protein Similarity: 100 99.9 79 73.8 N.A. 89 40.4 N.A. N.A. 43.5 72.7 63.9 N.A. 55.4 52 42.5 42.8
P-Site Identity: 100 100 0 86.6 N.A. 73.3 6.6 N.A. N.A. 13.3 66.6 13.3 N.A. 26.6 6.6 0 0
P-Site Similarity: 100 100 20 93.3 N.A. 86.6 13.3 N.A. N.A. 26.6 86.6 33.3 N.A. 46.6 33.3 6.6 6.6
Percent
Protein Identity: 32.9 N.A. N.A. 31.9 27.2 27.5
Protein Similarity: 52.3 N.A. N.A. 51.5 48.6 45.5
P-Site Identity: 20 N.A. N.A. 6.6 6.6 6.6
P-Site Similarity: 40 N.A. N.A. 26.6 20 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 18 48 0 0 0 0 12 6 18 0 6 12 0 6 6 % A
% Cys: 0 0 0 6 0 0 0 0 0 6 0 0 0 0 0 % C
% Asp: 6 6 0 0 0 6 0 0 6 12 0 0 0 12 30 % D
% Glu: 6 6 6 18 0 0 0 0 12 18 30 6 6 12 6 % E
% Phe: 6 0 0 0 0 0 0 0 0 0 0 6 12 0 0 % F
% Gly: 6 0 6 12 6 12 6 6 6 6 6 6 6 0 6 % G
% His: 0 6 0 0 6 0 0 0 0 0 6 0 0 0 0 % H
% Ile: 6 12 6 0 6 0 6 12 12 0 6 0 0 0 6 % I
% Lys: 0 0 6 30 6 12 18 6 0 12 6 0 0 24 0 % K
% Leu: 0 0 0 0 42 48 0 0 0 18 18 12 18 0 0 % L
% Met: 6 0 0 0 0 0 0 0 0 0 6 0 0 6 0 % M
% Asn: 0 0 6 6 6 6 18 6 0 12 0 0 0 0 0 % N
% Pro: 6 6 0 6 0 0 6 6 0 0 0 6 6 0 0 % P
% Gln: 6 6 6 6 6 0 6 6 6 0 0 12 0 12 6 % Q
% Arg: 0 6 6 18 0 0 0 0 6 6 0 0 0 12 12 % R
% Ser: 6 0 36 0 6 6 6 18 0 0 6 12 0 12 18 % S
% Thr: 30 0 12 0 6 6 12 30 0 6 6 30 42 0 6 % T
% Val: 0 6 12 0 6 0 12 6 36 6 6 0 12 6 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 6 6 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _